In terminology, living chemical reaction, as opposed to a nonliving chemical reaction, refers, hypothetically, to a “chemical reaction” that is “alive”.
Overview
In 1925, Gilbert Lewis, in his §7 “Non-Mathematical Sciences”, of his Anatomy of Science, attempted to digress on the what he referred to as the “missing link connecting the animate with the inanimate”, i.e. connecting the evolution of “living organisms” originating from chemicals governed by physics, chemistry, and thermodynamics; after discussing how crystals have the power of reproduction, autocatalysis, and other standard “emergence” patch solutions, he ruminates on whether him writing a book was but a “chemical reaction”, the gist of which is as follows: [1]
“Suppose that this hypothetical experiment could be realized, which seems not unlikely, and suppose we could discover a whole chain of phenomena [evolution timeline], leading by imperceptible gradations form the simplest chemical molecule to the most highly developed organism [human molecule]. Would we then say that my preparation of this volume [Anatomy of Science] is only a chemical reaction [extrapolate up approach], or, conversely that a crystal is thinking [extrapolate down approach] about the concepts of science? Nothing could be more absurd, and I once more express the hope that in attacking the infallibility of categories I have not seemed to intimate that they are the less to be respected because they are not absolute. The interaction between two bodies is treated by methods of mechanics; the interaction of a billion such bodies must be treated by the statistical methods of thermodynamics.”
“The science of physics rests on the postulate of determinism; the science of biology, unless it is to ignore deliberately the phenomenon of behavior, must abandon this postulate and substitute therefor a postulate of choice or freedom. Perhaps our genius for unity will some time produce a science so broad as to include the behavior of a group of electrons and the behavior of a university faculty, but such a possibility seems now so remote that I for one would hesitate to guess whether this wonderful science would be more like mechanics or like a psychology.”
A + B → C + D
Reactants → Products
Nonliving Nonliving Nonliving ? Living Living Living Reactants → Products Reactants → Products Reactants → Products Reactants → Products Reactants → Products Reactants → Products Reactants → Products
“The animal cell, which is called ‘alive,” is simply a living chemical reaction—or more exactly a living oxidation of carbon—that is to say, an oxidation of carbon which has organized itself by the creation of services of entry and exit of materials of reaction, precisely as we organize our factories industrially.”— Ernest Solvay (1910) “The Living Body as a Factory” (ΡΊ), Lecture to the Belgian Association of Engineer; in: Revue Scientifique, Paris Dec 3.
“Nonliving chemical reactions are driven by thermodynamics (heat) explore the possibilities open to them in an ergodic fashion—that is, by a process in which every exploratory sequence is the same. Life, on the other hand, explores its possibilities through evolution. It accumulates information—first in genes, then in memory—to help guide its search down narrower and more productive paths. How and when did information come to dominate the energetic processes of the physical world, and in doing so give rise to life?”— Robert Frenay (2006), Pulse [2]